Notícias e Actualidades

SARS-CoV-2 Corona Virus: COVID-19 and the Global Pandemic

Infection Control Today, July 2025

https://www.infectioncontroltoday.com/view/sars-cov-2-corona-virus-covid-19-and-the-global-pandemic

In the conversation of viruses, COVID-19's ongoing impact cannot be ignored. Although hospitalizations and deaths have decreased, the virus continues to circulate, especially among the immunocompromised and elderly. Learn how the virus spreads, how new strains are monitored, and why "long COVID" and new animal-human transmission threats like HKU5-CoV2 keep COVID-19 in the public health spotlight.


Long covid outcomes at one year after mild SARS-CoV-2 infection: nationwide cohort study

BMJ, British Medical Journal, Published 11 January 2023

https://www.bmj.com/content/380/bmj-2022-072529

Fig 2- Risk for long term health outcomes after SARS-CoV-2 infection in patients with mild disease. Hazard ratios and risk differences per 10 000 patients of reported health outcomes (persistent symptoms) in unvaccinated SARS-CoV-2 infected patients with mild covid-19 during early and late periods

BMJ, Januray 2023

Fig 3 - Risk for long term health outcomes after SARS-CoV-2 infection in patients with mild disease. Hazard ratios and risk differences per 10 000 patients of reported health outcomes (acute diagnoses, infectious diseases, chronic conditions) in unvaccinated SARS-CoV-2 infected patients with mild covid-19 during early and late periods. TIA=transient ischaemic attack, BMJ, Jan 2023


Here's what we know about the new Omicron variant XBB.1.5

Gavi, The Vaccine Alliance, published, 6 January 23

https://www.gavi.org/vaccineswork/heres-what-we-know-about-new-omicron-variant-xbb15


How long after I get COVID-19 will I test negative?

Gavi, The Vaccine Alliance, published, September 22

https://www.gavi.org/vaccineswork/how-long-after-i-get-covid-19-will-i-test-negative?gclid=EAIaIQobChMI5evOuuOw-gIVFvN3Ch2tngNYEAAYASAAEgKXpvD_BwE


COVID-19 vaccination protects against Long COVID

Gavi, The Vaccine alliance, published September 2022

https://www.gavi.org/vaccineswork/covid-19-vaccination-protects-against-long-covid


Another new COVID variant is spreading - here's what we know about omicron BA.4.6

Gavi, The Vaccine alliance, published September 2022

https://www.gavi.org/vaccineswork/another-new-covid-variant-spreading-heres-what-we-know-about-omicron-ba46 


COVID-19: latest safety data provide reassurance about use of mRNA vaccines during pregnancy

EMA (European Medicines agency), published 18/01/2022

https://www.ema.europa.eu/en/news/covid-19-latest-safety-data-provide-reassurance-about-use-mrna-vaccines-during-pregnancy


WHO recommends two new drugs to treat COVID-19

WHO, published 14 January 2022

https://www.who.int/news/item/14-01-2022-who-recommends-two-new-drugs-to-treat-covid-19


Asthma, allergies may reduce COVID-19 risk

Medical News Today, published December 13, 2021

https://www.medicalnewstoday.com/articles/asthma-allergies-may-reduce-covid-19-risk


Sotrovimab for Early Covid-19

The New England Journal of Medicine, publishe 18

Disponível em:




Seven COVID-19 symptoms you shouldn't ignore

Gavi, The Vaccine Alliance, published 29 September 2021

https://www.gavi.org/vaccineswork/seven-covid-19-symptoms-you-shouldnt-ignore?fbclid=IwAR3XohoAOcte0motTHhmRG1zcEprNv7s_Rht1i57Ts7X8B0ddEw3apyIWqQ


Common hypertension drug may help treat severe COVID-19

Medical News Today, published 10 September 2021

https://www.medicalnewstoday.com/articles/common-hypertension-drug-may-help-treat-severe-covid-19


Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing

BMJ, published 27 August 2021

https://www.bmj.com/content/374/bmj.n1931

The BMJ, 28 August 2021


How COVID-19 will change the management of other respiratory viral infections

Intensive Care Medicine, published August 2021

https://link.springer.com/article/10.1007/s00134-021-06491-2

Examples of what questions were raised during COVID-19 pandemic that would need to be addressed regarding other respiratory viral infections (RVIs). HFNO: high-flow nasal oxygen, NIV: noninvasive ventilation (NIV), ECMO: extracorporeal membrane oxygenation, RCT: randomized controlled trial

From: How COVID-19 will change the management of other respiratory viral infections, 

Arabi, Y.M., Derde, L.P.G. & Timsit, JF. How COVID-19 will change the management of other respiratory viral infections. Intensive Care Med (2021). https://doi.org/10.1007/s00134-021-06491-2



Covid-19 booster vaccines: What we know and who's doing what

BMJ, Published 20 August 2021

https://www.bmj.com/content/374/bmj.n2082


How will COVID vaccines work on compromised immune systems? Here's what we know

Gavi, The Vaccine Alliance, published 11 August 2021

https://www.gavi.org/vaccineswork/how-will-covid-vaccines-work-compromised-immune-systems-heres-what-we-know


Can dogs be trained to sniff out COVID-19?

Gavi, The Vaccine Alliance, published 13 July 2021



How effective are COVID-19 vaccines in the real-world?

Gavi, The Vaccine Alliance, published 23 July 2021

https://www.gavi.org/vaccineswork/how-effective-are-covid-19-vaccines-real-world


CDC Tightens Masking Rules for Fully Vaccinated in COVID-19 Hot Spots

Infection Control Today, published July 27, 2021

https://www.infectioncontroltoday.com/view/cdc-expected-to-tighten-masking-rules-for-fully-vaccinated


Long covid-mechanisms, risk factors, and management

BMJ, Published 26 July 2021

https://www.bmj.com/content/374/bmj.n1648


Lambda Variant of COVID-19 Might Be Resistant to Vaccines

Infection Control Today, published 26 July 2021

https://www.infectioncontroltoday.com/view/lambda-variant-of-covid-19-might-be-resistant-to-vaccines


COVID-19 vaccine Spikevax approved for children aged 12 to 17 in EU

EMA, published 23 July 2021
 https://www.ema.europa.eu/en/news/covid-19-vaccine-spikevax-approved-children-aged-12-17-eu


EMA starts evaluating the use of Kineret in adult COVID-19 patients at increased risk of severe respiratory failure

 EMA, published 19 July 2021
 https://www.ema.europa.eu/en/news/ema-starts-evaluating-use-kineret-adult-covid-19-patients-increased-risk-severe-respiratory-failure


COVID-19-Associated Mucormycosis: Triple Threat of the Pandemic

American Society for Microbiology, published 15 July 2021

https://asm.org/Articles/2021/July/COVID-19-Associated-Mucormycosis-Triple-Threat-of



EMA and ECDC update on COVID-19

EMA, News 14/07/2021

https://www.ema.europa.eu/en/news/ema-ecdc-update-covid-19


Pfizer COVID vaccine shows 78% efficacy in pregnancy

CIDRAP - Center for Infectious Disease Research and Policy, published July 13 2021

https://www.cidrap.umn.edu/news-perspective/2021/07/pfizer-covid-vaccine-shows-78-efficacy-pregnancy


Could a universal coronavirus vaccine soon be a reality?

GAVI, the vaccine Alliance, 13 Jully 2021

https://www.gavi.org/vaccineswork/could-universal-coronavirus-vaccine-soon-be-reality


COVID: lambda variant is now in 29 countries, but what evidence do we have that it's more dangerous?

GAVI, the vaccine Alliance, 13 Jully 2021

https://www.gavi.org/vaccineswork/covid-lambda-variant-now-29-countries-what-evidence-do-we-have-its-more-dangerous


The world will not exit Covid-19 pandemic without booster shots, vaccine developer says

STAT, 13 July 2021

https://www.statnews.com/2021/07/13/the-world-will-not-exit-covid-19-pandemic-without-booster-shots-vaccine-developer-says/


When and how will we know if we need Covid-19 booster shots?

STAT,  12 July 2021

https://www.statnews.com/2021/07/12/when-and-how-will-we-know-covid-19-booster-shots/


CDC, FDA contradict Pfizer on COVID-19 vaccine booster

CIDRAP - Center for Infectious Disease Research and Policy, published July 9 2021

https://www.cidrap.umn.edu/news-perspective/2021/07/cdc-fda-contradict-pfizer-covid-19-vaccine-booster


Persistent symptoms in adult patients one year after COVID-19: a prospective cohort study

Clinical Infectious Diseases, Oxford Academic, University of Oxford, published   05 July 2021

https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab611/6315216


Five things we know about the Delta variant (and two things we don't)

GAVI, The Vaccine Alliance, published 16 June 2021

https://www.gavi.org/vaccineswork/five-things-we-know-about-delta-coronavirus-variant-and-two-things-we-still-need


How to give a COVID-mitigated hug

GAVI, The Vaccine Alliance, published 26 May 2021

https://www.gavi.org/vaccineswork/how-give-covid-mitigated-hug


Can we stop wearing masks after being vaccinated?

GAVI, The Vaccine Alliance, published 21 May 2021

https://www.gavi.org/vaccineswork/can-we-stop-wearing-masks-after-being-vaccinated


Covid-19: UK cases of variant from India rise by 160% in a week

BMJ, Published 21 May 2021

https://www.bmj.com/content/373/bmj.n1315


Fighting the flu: 100 years of preparing for pandemics

GAVI, The Vaccine Aliance, published May 18, 2021

https://www.gavi.org/vaccineswork/fighting-flu-100-years-preparing-pandemics


Antivirals against SARS-CoV-2 by autumn?

BMJ, published, 17 May 2021

https://www.bmj.com/content/373/bmj.n1215


The Next Pandemic: Another coronavirus?

GAVI, The Vaccine Alliance, published 06 May 2021 

https://www.gavi.org/vaccineswork/next-pandemic/another-coronavirus


Where are we with drug treatments for covid-19?

BMJ, Published 06 May 2021

https://www.bmj.com/content/bmj/373/bmj.n1109.full.pdf


EMA starts rolling review of COVID-19 Vaccine (Vero Cell) Inactivated

European Medicines Agency, published 04 May 2021

https://www.ema.europa.eu/en/news/ema-starts-rolling-review-covid-19-vaccine-vero-cell-inactivated


The Pandemic Within the Pandemic

GAVI, The Vaccine Aliance, published April 30, 2021

https://www.gavi.org/vaccineswork/pandemic-within-pandemic


Covid-19: What do we know about airborne transmission of SARS-CoV-2?

BMJ, published 22 April 2021

https://www.bmj.com/content/373/bmj.n1030


Ten scientific reasons in support of airborne transmission of SARS-CoV-2

The Lancet, published April 15, 2021

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00869-2/fulltext


Improving indoor ventilation and air quality will help us all to stay safe

BMJ, Published 14 April 2021

https://www.bmj.com/content/373/bmj.n913


The Potential Future of the COVID-19 Pandemic

Will SARS-CoV-2 Become a Recurrent Seasonal Infection?

Jama, published March 3, 2021

https://jamanetwork.com/journals/jama/fullarticle/2777343


Coronavirus Variants and Vaccines

JAMA, published 07 April 2021


Does the AstraZeneca COVID-19 vaccine really cause blood clots?

Various countries have halted the use of the Oxford-AstraZeneca vaccine while reports of blood clots are investigated. Here's what we know so far.

GAVI, Global Alliance Vaccine, Published March 16 2021

https://www.gavi.org/vaccineswork/does-astrazeneca-covid-19-vaccine-really-cause-blood-clots


A Pandemic year - A viral tsunami: How the underestimated coronavirus took over the world

The Washington Post, March 2021

https://www.washingtonpost.com/health/2021/03/09/coronavirus-spread-world/?arc404=true


Evolução do número de casos de Covid-19 em Portugal

relatório de nowcasting

Covid-19: curva epidémica e parâmetros de transmissibilidade

Instituto Nacional de Saúde Dr Ricardo Jorge, 12 de Março de 2021

https://www.insa.min-saude.pt/wp-content/uploads/2021/03/Report_covid19_12_03_2021.pdf


Ready for the Next Pandemic? (Spoiler Alert: It's Coming)

Infection control Today , 1 March 2021

https://www.infectioncontroltoday.com/view/ready-for-the-next-pandemic-spoiler-alert-it-s-coming-


The Long View: 100 years and counting of mask wearing in Japan

GAVI, published 19 February 2021

https://www.gavi.org/vaccineswork/long-view-100-years-and-counting-mask-wearing-japan



"Test and Standard Precautions"-Is It Enough to Protect Us From False-Negative Severe Acute Respiratory Syndrome Coronavirus 2 Test Results?

Anesthesia & Analgesia: March 2021 - Volume 132 - Issue 3 - p 616-621

https://journals.lww.com/anesthesia-analgesia/Fulltext/2021/03000/_Test_and_Standard_Precautions__Is_It_Enough_to.4.aspx

Graphic representation of the number of patients testing falsely negative and admitted to the operating room. The authors' (A.B. and S.J.) hospital treats approximately 20,000 patients in the operating room, or approximately 76 per working day (260 d/y). Assuming a prevalence of 0.15, an RT-PCR test specificity of 1 and sensitivity of 0.7 results in 4 patients infected with SARS-CoV-2 but testing falsely negative admitted to the operating room each day. Green indicates an infected patient who tests positive. Red indicates an infected patient who tests falsely negative. RT-PCR indicates reverse transcription-polymerase chain reaction; SARS-COV-2, severe acute respiratory syndrome coronavirus 2.

Anesthesia & Analgesia: March 2021 - Volume 132 - Issue 3 - p 616-621 - doi: 10.1213/ANE.000000000000535


Covid-19: Are cloth masks still effective? And other questions answered

BMJ, Published 15 February 2021

https://www.bmj.com/content/372/bmj.n432


PARECER DA SOCIEDADE PORTUGUESA DE PNEUMOLOGIA EM RELAÇÃO ÀS MÁSCARAS DE PROTEÇÃO CONTRA A COVID-19

https://www.sppneumologia.pt/noticias/parecer-da-sociedade-portuguesa-de-pneumologia-em-relacao-as-mascaras-de-protecao-contra-a-covid-19


Covid-19: Doctors' leaders call for revised PPE guidance to reflect new variants

BMJ, Published 15 January 2021 

https://www.bmj.com/content/372/bmj.n146

Vacina Covid e imunossupressão: FAQ's

International Academy for Clinical Hematology - ASTCT

https://www.hematology.org/covid-19/ash-astct-covid-19-and-vaccines


Taking Immunosuppressants? Fauci Says Get the COVID-19 Vaccine

AJMC, Published December 6, 2020

https://www.ajmc.com/view/taking-immunosuppressants-fauci-says-get-the-covid-19-vaccine

There's a new strain of COVID-19 - should we worry?

Viruses mutate all the time, but this new mutation affects the viral protein that invades human cells. What does this mean for the pandemic and the vaccine?

Gavi, the Vaccine Alliance, published 18 December 2020

https://www.gavi.org/vaccineswork/theres-new-strain-covid-19-should-we-worry



Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

JAMA, Published online September 03, 2020

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2770157


Perioperative Considerations for Tracheostomies in the Era of COVID-19

Published, Anesth Analg. 2020 June  

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273938/


COVID-19 Linked to Increased Risk for Parkinson's 

Medscape, published 05 November 2020

https://www.medscape.com/viewarticle/940464?src=soc_fb_201106_mscpedt_news_mdscp_parkinsons&faf=1
 



Trials of Oxford coronavirus vaccine begin in Kenya

Oxford University, published 30 October 2020

https://www.ox.ac.uk/news/2020-10-30-trials-oxford-coronavirus-vaccine-begin-kenya#


Covid-19: risks to healthcare workers and their families

BMJ, Published 28 October 2020

https://www.bmj.com/content/371/bmj.m3944


Aerosols vs. Droplets: In Transmitting COVID-19, There's a Big Difference


Previsões sobre o Futuro da Pandemia

Acta Medica Portuguesa, Outubro 2020 


Covid-19: Remdesivir has little or no impact on survival, WHO trial shows

BMJ, Published 19 October 2020

https://www.bmj.com/content/371/bmj.m4057


Manifestações Neurológicas e COVID-19

Acta Medica Portuguesa, Outubro 2020


The Gavi COVAX AMC Explained

The COVAX Facility is designed to benefit all participating countries and economies. It provides a lifeline to the majority of countries that would otherwise have limited or no access at all to COVID-19 vaccines

Gavi, The Vaccine Alliance, 13 Octob 2020

https://www.gavi.org/vaccineswork/gavi-covax-amc-explained


Long covid could be four different syndromes, review suggests


BMJ, published  14 October 2020

https://www.bmj.com/content/371/bmj.m3981


Oxford scientists develop extremely rapid diagnostic test for Covid-19

Oxford University, published 15 October 2020

https://www.ox.ac.uk/news/2020-10-15-oxford-scientists-develop-extremely-rapid-diagnostic-test-covid-19

Covid-19: O lançamento da vacina pode levar um ano e exigirá decisões de priorização difíceis

BMJ, publicado em 01 de outubro de 2020 

https://www.bmj.com/content/371/bmj.m3846


COVID-19 Airway Management: Expert Tips on Infection Control

Medscpe, September 25, 2020 

https://www.medscape.com/viewarticle/938064


Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2

N Engl J Med, published 28 september 2020 

https://www.nejm.org/doi/full/10.1056/NEJMc2016359


Covid-19: Do many people have pre-existing immunity?

BMJ, Published 17 September 2020 

https://www.bmj.com/content/370/bmj.m3563


Understanding Covid-19, transmission, informing control

University of Oxford


What Is COVID-19?

JAMA, Published online August 25, 2020

 https://jamanetwork.com/journals/jama/fullarticle/2768390


Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)A Review

JAMA. Published online August 25, 2020 

https://jamanetwork.com/journals/jama/fullarticle/2768391?resultClick=24


Covid-19: Hong Kong scientists report first confirmed case of reinfection

BMJ, (Published 26 August 2020)

https://www.bmj.com/content/370/bmj.m3340 



The Great Coronavirus Pandemic of 2020-7 Critical Lessons

JAMA ; 2020 Jun 30

https://jamanetwork.com/channels/health-forum/fullarticle/2769600?resultClick=1


COVID-19 and DexamethasoneA Potential Strategy to Avoid Steroid-Related Strongyloides Hyperinfection

JAMA. Published online July 30, 2020 

https://jamanetwork.com/journals/jama/fullarticle/2769100



More than 150 countries engaged in COVID-19 vaccine global access facility

WHO, 15 July 2020 News release Geneva/London 

https://www.who.int/news-room/detail/15-07-2020-more-than-150-countries-engaged-in-covid-19-vaccine-global-access-facility


Life and Death, Hope and Despair in the Era of Coronavirus Disease 2019

JAMA Cardiol. Published online July 8, 2020

https://jamanetwork.com/journals/jamacardiology/fullarticle/2768168


Covid-19: Airborne transmission is being underestimated, warn experts

BMJ, Published 07 July 2020) 

https://www.bmj.com/content/370/bmj.m2720


Developing a SARS-CoV-2 Vaccine at Warp Speed

JAMA. Published online July 6, 2020

https://jamanetwork.com/journals/jama/fullarticle/2768155


Dexamethasone in the management of covid -19

BMJ ,Published: 03 July 2020) 

https://www.bmj.com/content/370/bmj.m2648


Three Stages to COVID-19 Brain Damage, New Review Suggests

Medscape, June 29, 2020 

https://www.medscape.com/viewarticle/933131


Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

Nature Medicine, Published: 18 June 2020


Dexamethasone reduces death in hospitalised patients with severe respiratory complications of COVID-19

University of Oxford, June 16, 2020   

https://www.ox.ac.uk/news/2020-06-16-dexamethasone-reduces-death-hospitalised-patients-severe-respiratory-complications


Why COVID-19 Is a Threat to the Entire Nervous System

Jun 12, 2020 | Original story from Northwestern University 

https://www.technologynetworks.com/neuroscience/news/why-covid-19-is-a-threat-to-the-entire-nervous-system-336048


Covid-19: Hydroxychloroquine was ineffective as postexposure prophylaxis, study finds

BMJ (British Medical Journal), 05 June 2020

https://www.bmj.com/content/369/bmj.m2242


Investigadoras da FMUP/CINTESIS identificam 30 sintomas de Covid-19

Cintesis, FMUP,  5 de Junho 2020

https://noticias.up.pt/investigadoras-da-fmup-cintesis-identificam-30-sintomas-de-covid-19/


COVID-19 Neurological Effects: Does Virus Directly Attack the Brain?

Medscape, Medical News,  June, 03, 2020 

https://www.medscape.com/viewarticle/931658?src=soc_fb_200604_mscpedt_news_mdscp_coronavirus&faf=1


Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019

JAMA. Published online May 29, 2020

https://jamanetwork.com/journals/jamaneurology/fullarticle/2766766


Venous Thrombosis Among Critically Ill Patients With Coronavirus Disease 2019 (COVID-19)

JAMA. Published online May, 29 2020

https://jamanetwork.com/journals/jama/fullarticle/2765376


How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

JAMA. Published online April 27, 2020


Twentieth-Century Lessons for a Modern Coronavirus Pandemic

JAMA. Published online April 27, 2020 

https://jamanetwork.com/journals/jama/fullarticle/2765379


COVID-19 and Risks Posed to Personnel During Endotracheal Intubation

JAMA. Published online April 27, 2020 

https://jamanetwork.com/journals/jama/fullarticle/2765376


Management of COVID-19 Respiratory Distress

JAMA. Published online April 24, 2020 

https://jamanetwork.com/journals/jama/fullarticle/2765302


Mild or Moderate Covid-19

New England Journal of Medicine, April 24, 2020 

https://www.nejm.org/doi/full/10.1056/NEJMcp2009249?query=featured_coronavirus


Suporte ventilatório: guidelines da Sociedade Europeia de Medicina dos Cuidados Intensivos

https://covid19.newsfarma.pt/suporte-ventilatorio-guidelines-da-sociedade-europeia-de-medicina-dos-cuidados-intensivos/


Droplets and Aerosols in the Transmission of SARS-CoV-2

New England Journal of Medicine, April 15, 2020

https://www.nejm.org/doi/full/10.1056/NEJMc2009324


Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

JAMA. Published online April 13, 2020 

https://jamanetwork.com/journals/jama/fullarticle/2764727

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